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CIZ1-F, an alternatively spliced variant of the DNA replication protein CIZ1 with distinct expression and localisation, is overrepresented in early stage common solid tumours
CIZ1 promotes cyclin-dependent DNA replication and resides in sub-nuclear foci that are part of the protein nuclear matrix (NM), and in RNA assemblies that are enriched at the inactive X chromosome (Xi) in female cells. It is subjected to alternative splicing, with specific variants implicated in ad...
Autores principales: | Swarts, Dorian R.A., Stewart, Emma R., Higgins, Gillian S., Coverley, Dawn |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226236/ https://www.ncbi.nlm.nih.gov/pubmed/30280956 http://dx.doi.org/10.1080/15384101.2018.1526600 |
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