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R430: A potent inhibitor of DNA and RNA viruses

Acyclovir (ACV) is an effective antiviral agent for treating lytic Herpes Simplex virus, type 1 (HSV-1) infections, and it has dramatically reduced the mortality rate of herpes simplex encephalitis. However, HSV-1 resistance to ACV and its derivatives is being increasingly documented, particularly a...

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Detalles Bibliográficos
Autores principales: D’Aiuto, Leonardo, McNulty, James, Hartline, Caroll, Demers, Matthew, Kalkeri, Raj, Wood, Joel, McClain, Lora, Chattopadhyay, Ansuman, Zhi, Yun, Naciri, Jennifer, Smith, Adam, Yolken, Robert, Chowdari, Kodavali, Zepeda-Velazquez, Carlos, Dokuburra, Chanti Babu, Marques, Ernesto, Ptak, Roger, Kinchington, Paul, Watkins, Simon, Prichard, Mark, Bloom, David, Nimgaonkar, Vishwajit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226428/
https://www.ncbi.nlm.nih.gov/pubmed/30413769
http://dx.doi.org/10.1038/s41598-018-33904-y