Perineuronal nets decrease membrane capacitance of peritumoral fast spiking interneurons in a model of epilepsy

Brain tumor patients commonly present with epileptic seizures. We show that tumor-associated seizures are the consequence of impaired GABAergic inhibition due to an overall loss of peritumoral fast spiking interneurons (FSNs) concomitant with a significantly reduced firing rate of those that remain....

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Detalles Bibliográficos
Autores principales: Tewari, Bhanu P., Chaunsali, Lata, Campbell, Susan L., Patel, Dipan C., Goode, Adam E., Sontheimer, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226462/
https://www.ncbi.nlm.nih.gov/pubmed/30413686
http://dx.doi.org/10.1038/s41467-018-07113-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226462/
https://www.ncbi.nlm.nih.gov/pubmed/30413686
http://dx.doi.org/10.1038/s41467-018-07113-0

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