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Ongoing human chromosome end extension revealed by analysis of BioNano and nanopore data

The majority of human chromosome ends remain incompletely assembled due to their highly repetitive structure. In this study, we use BioNano data to anchor and extend chromosome ends from two European trios as well as two unrelated Asian genomes. At least 11 BioNano assembled chromosome ends are stru...

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Detalles Bibliográficos
Autores principales: Shao, Haojing, Zhou, Chenxi, Cao, Minh Duc, Coin, Lachlan J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226469/
https://www.ncbi.nlm.nih.gov/pubmed/30413723
http://dx.doi.org/10.1038/s41598-018-34774-0