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Cardol triene inhibits dengue infectivity by targeting kl loops and preventing envelope fusion

Dengue virus causes a global burden that specific chemotherapy has not been established. A previous report suggested that anacardic acid inhibited hepatitis C virus infection. Here, we explored structure activity relationship of anacardic acid, cardanol, and cardol homologues with anti-DENV cellular...

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Detalles Bibliográficos
Autores principales: Kanyaboon, Parichat, Saelee, Thanaphon, Suroengrit, Aphinya, Hengphasatporn, Kowit, Rungrotmongkol, Thanyada, Chavasiri, Warinthorn, Boonyasuppayakorn, Siwaporn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226472/
https://www.ncbi.nlm.nih.gov/pubmed/30413789
http://dx.doi.org/10.1038/s41598-018-35035-w