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Transcriptome-wide identification of transient RNA G-quadruplexes in human cells

Guanine-rich RNA sequences can fold into four-stranded structures, termed G-quadruplexes (G4-RNAs), whose biological roles are poorly understood, and in vivo existence is debated. To profile biologically relevant G4-RNA in the human transcriptome, we report here on G4RP-seq, which combines G4-RNA-sp...

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Detalles Bibliográficos
Autores principales: Yang, Sunny Y., Lejault, Pauline, Chevrier, Sandy, Boidot, Romain, Robertson, A. Gordon, Wong, Judy M. Y., Monchaud, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226477/
https://www.ncbi.nlm.nih.gov/pubmed/30413703
http://dx.doi.org/10.1038/s41467-018-07224-8