Oral Pathobiont Activates Anti-Apoptotic Pathway, Promoting both Immune Suppression and Oncogenic Cell Proliferation

Chronic periodontitis (CP) is a microbial dysbiotic disease linked to increased risk of oral squamous cell carcinomas (OSCCs). To address the underlying mechanisms, mouse and human cell infection models and human biopsy samples were employed. We show that the ‘keystone’ pathogen Porphyromonas gingiv...

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Detalles Bibliográficos
Autores principales: Arjunan, Pachiappan, Meghil, Mohamed M., Pi, Wenhu, Xu, Jinxian, Lang, Liwei, El-Awady, Ahmed, Sullivan, William, Rajendran, Mythilypriya, Rabelo, Mariana Sousa, Wang, Tong, Tawfik, Omnia K., Kunde-Ramamoorthy, Govindarajan, Singh, Nagendra, Muthusamy, Thangaraju, Susin, Cristiano, Teng, Yong, Arce, Roger M., Cutler, Christopher W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226501/
https://www.ncbi.nlm.nih.gov/pubmed/30413788
http://dx.doi.org/10.1038/s41598-018-35126-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226501/
https://www.ncbi.nlm.nih.gov/pubmed/30413788
http://dx.doi.org/10.1038/s41598-018-35126-8

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