Inflammation-induced Id2 promotes plasticity in regulatory T cells

T(H)17 cells originating from regulatory T (T(reg)) cells upon loss of the T(reg-)specific transcription factor Foxp3 accumulate in sites of inflammation and aggravate autoimmune diseases. Whether an active mechanism drives the generation of these pathogenic ‘ex-Foxp3 T(H)17’ cells, remains unclear....

Descripción completa

Detalles Bibliográficos
Autores principales: Hwang, Sung-Min, Sharma, Garima, Verma, Ravi, Byun, Seohyun, Rudra, Dipayan, Im, Sin-Hyeog
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226514/
https://www.ncbi.nlm.nih.gov/pubmed/30413714
http://dx.doi.org/10.1038/s41467-018-07254-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226514/
https://www.ncbi.nlm.nih.gov/pubmed/30413714
http://dx.doi.org/10.1038/s41467-018-07254-2

Ejemplares similares