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Embryonic Stem Cells Derived Kidney Organoids as Faithful Models to Target Programmed Nephrogenesis

The kidney is a complex organ that is comprised of thousands of nephrons developing through reciprocal inductive interactions between metanephric mesenchyme (MM) and ureteric bud (UB). The MM undergoes mesenchymal to epithelial transition (MET) in response to the signaling from the UB. The secreted...

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Detalles Bibliográficos
Autores principales: Tan, Zenglai, Shan, Jingdong, Rak-Raszewska, Aleksandra, Vainio, Seppo J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226521/
https://www.ncbi.nlm.nih.gov/pubmed/30413738
http://dx.doi.org/10.1038/s41598-018-34995-3