The geranyl acetophenone tHGA attenuates human bronchial smooth muscle proliferation via inhibition of AKT phosphorylation

Increased airway smooth muscle (ASM) mass is a prominent hallmark of airway remodeling in asthma. Inhaled corticosteroids and long-acting beta(2)-agonists remain the mainstay of asthma therapy, however are not curative and ineffective in attenuating airway remodeling. The geranyl acetophenone 2,4,6-...

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Detalles Bibliográficos
Autores principales: Yap, Hui Min, Lee, Yu Zhao, Harith, Hanis Hazeera, Tham, Chau Ling, Cheema, Manraj Singh, Shaari, Khozirah, Israf, Daud Ahmad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226528/
https://www.ncbi.nlm.nih.gov/pubmed/30413753
http://dx.doi.org/10.1038/s41598-018-34847-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226528/
https://www.ncbi.nlm.nih.gov/pubmed/30413753
http://dx.doi.org/10.1038/s41598-018-34847-0

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