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Age stratification corrects bias in estimated hazard of APOE genotype for Alzheimer's disease
INTRODUCTION: The apolipoprotein E (APOE) e4 allele is a major genetic risk factor of late-onset Alzheimer's disease. However, its interaction with two other canonical risk factors, age and sex, is not clear. Previous studies have reported conflicting results on its differential effects in men...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226550/ https://www.ncbi.nlm.nih.gov/pubmed/30450407 http://dx.doi.org/10.1016/j.trci.2018.09.006 |