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Age stratification corrects bias in estimated hazard of APOE genotype for Alzheimer's disease

INTRODUCTION: The apolipoprotein E (APOE) e4 allele is a major genetic risk factor of late-onset Alzheimer's disease. However, its interaction with two other canonical risk factors, age and sex, is not clear. Previous studies have reported conflicting results on its differential effects in men...

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Detalles Bibliográficos
Autores principales: Liu, Li, Caselli, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226550/
https://www.ncbi.nlm.nih.gov/pubmed/30450407
http://dx.doi.org/10.1016/j.trci.2018.09.006

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