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A Simplified System to Express Circularized Inhibitors of miRNA for Stable and Potent Suppression of miRNA Functions
MicroRNAs (miRNAs) are an evolutionarily conserved class of small regulatory noncoding RNAs, binding to complementary target mRNAs and resulting in mRNA translational inhibition or degradation, and they play an important role in regulating many aspects of physiologic and pathologic processes in mamm...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226557/ https://www.ncbi.nlm.nih.gov/pubmed/30414569 http://dx.doi.org/10.1016/j.omtn.2018.09.025 |