Cargando…

A Simplified System to Express Circularized Inhibitors of miRNA for Stable and Potent Suppression of miRNA Functions

MicroRNAs (miRNAs) are an evolutionarily conserved class of small regulatory noncoding RNAs, binding to complementary target mRNAs and resulting in mRNA translational inhibition or degradation, and they play an important role in regulating many aspects of physiologic and pathologic processes in mamm...

Descripción completa

Detalles Bibliográficos
Autores principales: Shu, Yi, Wu, Ke, Zeng, Zongyue, Huang, Shifeng, Ji, Xiaojuan, Yuan, Chengfu, Zhang, Linghuan, Liu, Wei, Huang, Bo, Feng, Yixiao, Zhang, Bo, Dai, Zhengyu, Shen, Yi, Luo, Wenping, Wang, Xi, Liu, Bo, Lei, Yan, Ye, Zhenyu, Zhao, Ling, Cao, Daigui, Yang, Lijuan, Chen, Xian, Luu, Hue H., Reid, Russell R., Wolf, Jennifer Moriatis, Lee, Michael J., He, Tong-Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226557/
https://www.ncbi.nlm.nih.gov/pubmed/30414569
http://dx.doi.org/10.1016/j.omtn.2018.09.025