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Angpt2 Induces Mesangial Cell Apoptosis through the MicroRNA-33-5p-SOCS5 Loop in Diabetic Nephropathy

Diabetic nephropathy (DN) is the leading cause of end-stage renal disease. Mesangial cell (MC) loss is correlated with worsening renal function in DN. Disturbance of angiopoietin (Angpt)/Tie ligand-receptor system causes inflammation and abnormal angiogenesis. This association between elevated circu...

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Detalles Bibliográficos
Autores principales: Tsai, Yi-Chun, Kuo, Po-Lin, Hung, Wei-Wen, Wu, Ling-Yu, Wu, Ping-Hsun, Chang, Wei-An, Kuo, Mei-Chuan, Hsu, Ya-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226567/
https://www.ncbi.nlm.nih.gov/pubmed/30414568
http://dx.doi.org/10.1016/j.omtn.2018.10.003