Inhibition of GLUT-1 expression and the PI3K/Akt pathway to enhance the chemosensitivity of laryngeal carcinoma cells in vitro

BACKGROUND: The mechanism of chemoresistance remains unknown. Here, we investigated if glucose transporter-1 (GLUT-1) and PI3K/Akt pathways are associated with the sensitivity to cisplatin in Hep-2 laryngeal carcinoma cells and whether the inhibition of GLUT-1 and the PI3K/Akt pathways enhances the...

Descripción completa

Detalles Bibliográficos
Autores principales: Jiang, Tao, Zhou, Min-Li, Fan, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6228052/
https://www.ncbi.nlm.nih.gov/pubmed/30464533
http://dx.doi.org/10.2147/OTT.S176818

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6228052/
https://www.ncbi.nlm.nih.gov/pubmed/30464533
http://dx.doi.org/10.2147/OTT.S176818

Ejemplares similares