Age-related deregulation of TDP-43 after stroke enhances NF-κB-mediated inflammation and neuronal damage

BACKGROUND: TDP-43 has been identified as a disease-associated protein in several chronic neurodegenerative disorders and increasing evidence suggests its potentially pathogenic role following brain injuries. Normally expressed in nucleus, under pathological conditions TDP-43 forms cytoplasmic ubiqu...

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Detalles Bibliográficos
Autores principales: Thammisetty, Sai Sampath, Pedragosa, Jordi, Weng, Yuan Cheng, Calon, Frédéric, Planas, Anna, Kriz, Jasna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230239/
https://www.ncbi.nlm.nih.gov/pubmed/30413172
http://dx.doi.org/10.1186/s12974-018-1350-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230239/
https://www.ncbi.nlm.nih.gov/pubmed/30413172
http://dx.doi.org/10.1186/s12974-018-1350-y

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