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Age-related deregulation of TDP-43 after stroke enhances NF-κB-mediated inflammation and neuronal damage
BACKGROUND: TDP-43 has been identified as a disease-associated protein in several chronic neurodegenerative disorders and increasing evidence suggests its potentially pathogenic role following brain injuries. Normally expressed in nucleus, under pathological conditions TDP-43 forms cytoplasmic ubiqu...
Autores principales: | Thammisetty, Sai Sampath, Pedragosa, Jordi, Weng, Yuan Cheng, Calon, Frédéric, Planas, Anna, Kriz, Jasna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230239/ https://www.ncbi.nlm.nih.gov/pubmed/30413172 http://dx.doi.org/10.1186/s12974-018-1350-y |
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