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Triple A patient cells suffering from mitotic defects fail to localize PGRMC1 to mitotic kinetochore fibers

BACKGROUND: Membrane-associated progesterone receptors are restricted to the endoplasmic reticulum and are shown to regulate the activity of cytochrome P450 enzymes which are involved in steroidogenesis or drug detoxification. PGRMC1 and PGRMC2 belong to the membrane-associated progesterone receptor...

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Detalles Bibliográficos
Autores principales: Jühlen, Ramona, Landgraf, Dana, Huebner, Angela, Koehler, Katrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230297/
https://www.ncbi.nlm.nih.gov/pubmed/30455725
http://dx.doi.org/10.1186/s13008-018-0041-5