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Potentiation of Antidepressant Effects of Agomelatine and Bupropion by Hesperidin in Mice

Hesperidin, a well-known flavanone glycoside mostly found in citrus fruits, showed neuroprotective and antidepressant activity. Agomelatine, a melatonergic MT(1)/MT(2) agonist and 5-HT(2C) receptor antagonist, exhibits good antidepressant efficacy. Bupropion has been widely used for the treatment of...

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Detalles Bibliográficos
Autores principales: Nadar, Jegan Sakthivel, Kale, Pravin Popatrao, Kadu, Pramod Kerunath, Prabhavalkar, Kedar, Dhangar, Ruchita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230398/
https://www.ncbi.nlm.nih.gov/pubmed/30510800
http://dx.doi.org/10.1155/2018/9828639