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Potentiation of Antidepressant Effects of Agomelatine and Bupropion by Hesperidin in Mice
Hesperidin, a well-known flavanone glycoside mostly found in citrus fruits, showed neuroprotective and antidepressant activity. Agomelatine, a melatonergic MT(1)/MT(2) agonist and 5-HT(2C) receptor antagonist, exhibits good antidepressant efficacy. Bupropion has been widely used for the treatment of...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230398/ https://www.ncbi.nlm.nih.gov/pubmed/30510800 http://dx.doi.org/10.1155/2018/9828639 |