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Vav proteins maintain epithelial traits in breast cancer cells using miR-200c-dependent and independent mechanisms

The bidirectional regulation of epithelial–mesenchymal transitions (EMT) is key in tumorigenesis. Rho GTPases regulate this process via canonical pathways that impinge on the stability of cell-to-cell contacts, cytoskeletal dynamics, and cell invasiveness. Here, we report that the Rho GTPase activat...

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Detalles Bibliográficos
Autores principales: Lorenzo-Martín, L. Francisco, Citterio, Carmen, Menacho-Márquez, Mauricio, Conde, Javier, Larive, Romain M., Rodríguez-Fdez, Sonia, García-Escudero, Ramón, Robles-Valero, Javier, Cuadrado, Myriam, Fernández-Pisonero, Isabel, Dosil, Mercedes, Sevilla, María A., Montero, María J., Fernández-Salguero, Pedro M., Paramio, Jesús M., Bustelo, Xosé R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230471/
https://www.ncbi.nlm.nih.gov/pubmed/30087437
http://dx.doi.org/10.1038/s41388-018-0433-7