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Imaging neurodegeneration in Down syndrome: brain templates for amyloid burden and tissue segmentation

The focus of Alzheimer’s disease (AD) neuroimaging research has shifted towards an investigation of the earliest stages of AD pathogenesis, which manifests in every young adult with Down syndrome (DS; trisomy 21) resulting from a deterministic genetic predisposition to amyloid precursor protein over...

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Detalles Bibliográficos
Autores principales: Lao, Patrick J., Handen, Ben L., Betthauser, Tobey J., Cody, Karly A., Cohen, Annie D., Tudorascu, Dana L., Stone, Charles K., Price, Julie C., Johnson, Sterling C., Klunk, William E., Christian, Bradley T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230506/
https://www.ncbi.nlm.nih.gov/pubmed/29752653
http://dx.doi.org/10.1007/s11682-018-9888-y