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Imaging neurodegeneration in Down syndrome: brain templates for amyloid burden and tissue segmentation
The focus of Alzheimer’s disease (AD) neuroimaging research has shifted towards an investigation of the earliest stages of AD pathogenesis, which manifests in every young adult with Down syndrome (DS; trisomy 21) resulting from a deterministic genetic predisposition to amyloid precursor protein over...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230506/ https://www.ncbi.nlm.nih.gov/pubmed/29752653 http://dx.doi.org/10.1007/s11682-018-9888-y |