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miRNA miR-21 Is Largely Dispensable for Intrathymic T-Cell Development

Development of T cells in the thymus is tightly controlled to continually produce functional, but not autoreactive, T cells. miRNAs provide a layer of post-transcriptional gene regulation to this process, but the role of many individual miRNAs in T-cell development remains unclear. miR-21 is promine...

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Detalles Bibliográficos
Autores principales: Kunze-Schumacher, Heike, Winter, Samantha J., Imelmann, Esther, Krueger, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230590/
https://www.ncbi.nlm.nih.gov/pubmed/30455689
http://dx.doi.org/10.3389/fimmu.2018.02497