ATF3 Sustains IL-22-Induced STAT3 Phosphorylation to Maintain Mucosal Immunity Through Inhibiting Phosphatases

In gut epithelium, IL-22 transmits signals through STAT3 phosphorylation (pSTAT3) which provides intestinal immunity. Many components in the IL-22-pSTAT3 pathway have been identified as risk factors for inflammatory bowel disease (IBD) and some of them are considered as promising therapeutic targets...

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Detalles Bibliográficos
Autores principales: Glal, Doaa, Sudhakar, Janaki N., Lu, Hsueh-Han, Liu, Ming-Che, Chiang, Hung-Yu, Liu, Yen-Chun, Cheng, Ching-Feng, Shui, Jr-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230592/
https://www.ncbi.nlm.nih.gov/pubmed/30455690
http://dx.doi.org/10.3389/fimmu.2018.02522

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230592/
https://www.ncbi.nlm.nih.gov/pubmed/30455690
http://dx.doi.org/10.3389/fimmu.2018.02522

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