Cargando…
BCR‐ABL exon 7 deletion and novel point mutation in patient with chronic myelogenous leukemia and TKI resistance
I report a novel BCR‐ABL point mutation c.844G>C p.E282Q and a case of combination of two BCR‐ABL point mutations (p.E282Q and p.L298R) and exon 7 deletion (del. c.1086‐1270) in TKI‐resistant patient. These point mutations were present only in a truncated transcript and were absent in “wild‐type”...
| Autor principal: | |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230594/ https://www.ncbi.nlm.nih.gov/pubmed/30455891 http://dx.doi.org/10.1002/ccr3.1794 |