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P7C3 Inhibits LPS-Induced Microglial Activation to Protect Dopaminergic Neurons Against Inflammatory Factor-Induced Cell Death in vitro and in vivo

Parkinson’s disease (PD) is the second most common neurodegenerative disorder. Although its pathogenesis remains unclear, growing evidencce suggests that microglia-mediated neuroinflammation contributes greatly to the progression of PD. P7C3, an aminopropyl carbazole, possesses significant neuroprot...

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Detalles Bibliográficos
Autores principales: Gu, Chao, Hu, Qingsong, Wu, Jiayuan, Mu, Chenchen, Ren, Haigang, Liu, Chun-Feng, Wang, Guanghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230654/
https://www.ncbi.nlm.nih.gov/pubmed/30455635
http://dx.doi.org/10.3389/fncel.2018.00400