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P7C3 Inhibits LPS-Induced Microglial Activation to Protect Dopaminergic Neurons Against Inflammatory Factor-Induced Cell Death in vitro and in vivo
Parkinson’s disease (PD) is the second most common neurodegenerative disorder. Although its pathogenesis remains unclear, growing evidencce suggests that microglia-mediated neuroinflammation contributes greatly to the progression of PD. P7C3, an aminopropyl carbazole, possesses significant neuroprot...
Autores principales: | Gu, Chao, Hu, Qingsong, Wu, Jiayuan, Mu, Chenchen, Ren, Haigang, Liu, Chun-Feng, Wang, Guanghui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230654/ https://www.ncbi.nlm.nih.gov/pubmed/30455635 http://dx.doi.org/10.3389/fncel.2018.00400 |
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