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Limited Foxp3(+) Regulatory T Cells Response During Acute Trypanosoma cruzi Infection Is Required to Allow the Emergence of Robust Parasite-Specific CD8(+) T Cell Immunity

While it is now acknowledged that CD4(+) T cells expressing CD25 and Foxp3 (Treg cells) regulate immune responses and, consequently, influence the pathogenesis of infectious diseases, the regulatory response mediated by Treg cells upon infection by Trypanosoma cruzi was still poorly characterized. I...

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Detalles Bibliográficos
Autores principales: Araujo Furlan, Cintia L., Tosello Boari, Jimena, Rodriguez, Constanza, Canale, Fernando P., Fiocca Vernengo, Facundo, Boccardo, Santiago, Beccaria, Cristian G., Adoue, Véronique, Joffre, Olivier, Gruppi, Adriana, Montes, Carolina L., Acosta Rodriguez, Eva V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230662/
https://www.ncbi.nlm.nih.gov/pubmed/30455700
http://dx.doi.org/10.3389/fimmu.2018.02555