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The Role of NLRP3 and IL-1β in the Pathogenesis of Inflammatory Bowel Disease

It is logical to assume that a major pro-inflammatory mechanism, i.e., the NLRP3 inflammasome would play a prominent role in the pathogenesis of the Inflammatory Bowel Disease (IBD) in humans. However, while both studies of murine models of gut disease and patients provide data that the main cytokin...

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Detalles Bibliográficos
Autores principales: Mao, Liming, Kitani, Atsushi, Strober, Warren, Fuss, Ivan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230716/
https://www.ncbi.nlm.nih.gov/pubmed/30455704
http://dx.doi.org/10.3389/fimmu.2018.02566