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Modification of betanodavirus virulence by substitutions in the 3' terminal region of RNA2

Betanodaviruses have bi-segmented positive-sense RNA genomes, consisting of RNAs 1 and 2. For some members of the related genus alphanodavirus, the 3′ terminal 50 nucleotides (nt) of RNA2, including a predicted stem-loop structure (3′SL), are essential for replication. We investigate the possible ex...

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Detalles Bibliográficos
Autores principales: Souto, Sandra, Olveira, José G., Dopazo, Carlos P., Borrego, Juan J., Bandín, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230769/
https://www.ncbi.nlm.nih.gov/pubmed/30041710
http://dx.doi.org/10.1099/jgv.0.001112