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Clinical pharmacology of alemtuzumab, an anti‐CD52 immunomodulator, in multiple sclerosis

Alemtuzumab, a humanized anti‐CD52 monoclonal antibody, is approved for treatment of relapsing multiple sclerosis (MS). In the Phase II/III trials, patients received 12 or 24 mg/day of alemtuzumab in two treatment courses (5 days for course 1 and 3 days for course 2), 12 months apart. Serum concentr...

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Detalles Bibliográficos
Autores principales: Li, Z., Richards, S., Surks, H. K., Jacobs, A., Panzara, M. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231011/
https://www.ncbi.nlm.nih.gov/pubmed/30144037
http://dx.doi.org/10.1111/cei.13208