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Clinical pharmacology of alemtuzumab, an anti‐CD52 immunomodulator, in multiple sclerosis
Alemtuzumab, a humanized anti‐CD52 monoclonal antibody, is approved for treatment of relapsing multiple sclerosis (MS). In the Phase II/III trials, patients received 12 or 24 mg/day of alemtuzumab in two treatment courses (5 days for course 1 and 3 days for course 2), 12 months apart. Serum concentr...
Autores principales: | Li, Z., Richards, S., Surks, H. K., Jacobs, A., Panzara, M. A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231011/ https://www.ncbi.nlm.nih.gov/pubmed/30144037 http://dx.doi.org/10.1111/cei.13208 |
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