Sunitinib-suppressed miR-452-5p facilitates renal cancer cell invasion and metastasis through modulating SMAD4/SMAD7 signals

PURPOSE: Although microRNAs (miRNAs) were revealed as crucial modulators in tumor metastasis and target therapy, our understanding of their roles in metastatic renal cell carcinoma (mRCC) and Sunitinib treatment was limited. Here we sought to identify human miRNAs that acted as key regulators in ren...

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Detalles Bibliográficos
Autores principales: Zhai, Wei, Li, Saiyang, Zhang, Jin, Chen, Yonghui, Ma, Junjie, Kong, Wen, Gong, Dongkui, Zheng, Junhua, Xue, Wei, Xu, Yunfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231268/
https://www.ncbi.nlm.nih.gov/pubmed/30419914
http://dx.doi.org/10.1186/s12943-018-0906-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231268/
https://www.ncbi.nlm.nih.gov/pubmed/30419914
http://dx.doi.org/10.1186/s12943-018-0906-x

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