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Clinical T Cell Receptor Repertoire Deep Sequencing and Analysis: An Application to Monitor Immune Reconstitution Following Cord Blood Transplantation

Spectratyping assays are well recognized as the clinical gold standard for assessing the T cell receptor (TCR) repertoire in haematopoietic stem cell transplant (HSCT) recipients. These assays use length distributions of the hyper variable complementarity-determining region 3 (CDR3) to characterize...

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Detalles Bibliográficos
Autores principales: Gkazi, Athina Soragia, Margetts, Ben K, Attenborough, Teresa, Mhaldien, Lana, Standing, Joseph F., Oakes, Theres, Heather, James M., Booth, John, Pasquet, Marlene, Chiesa, Robert, Veys, Paul, Klein, Nigel, Chain, Benny, Callard, Robin, Adams, Stuart P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231291/
https://www.ncbi.nlm.nih.gov/pubmed/30455696
http://dx.doi.org/10.3389/fimmu.2018.02547