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Clinical T Cell Receptor Repertoire Deep Sequencing and Analysis: An Application to Monitor Immune Reconstitution Following Cord Blood Transplantation
Spectratyping assays are well recognized as the clinical gold standard for assessing the T cell receptor (TCR) repertoire in haematopoietic stem cell transplant (HSCT) recipients. These assays use length distributions of the hyper variable complementarity-determining region 3 (CDR3) to characterize...
Autores principales: | Gkazi, Athina Soragia, Margetts, Ben K, Attenborough, Teresa, Mhaldien, Lana, Standing, Joseph F., Oakes, Theres, Heather, James M., Booth, John, Pasquet, Marlene, Chiesa, Robert, Veys, Paul, Klein, Nigel, Chain, Benny, Callard, Robin, Adams, Stuart P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231291/ https://www.ncbi.nlm.nih.gov/pubmed/30455696 http://dx.doi.org/10.3389/fimmu.2018.02547 |
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