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UGT1A1 (TA)(n) Promoter Genotype: Diagnostic and Population Pharmacogenetic Marker in Serbia

The UGT1A1 enzyme is involved in the metabolism of bilirubin and numerous medications. Unconjugated hyperbilirubinemia, commonly presented as Gilbert syndrome (GS), is a result of decreased activity of the UGT1A1 enzyme, variable number of TA repeats in the promoter of the UGT1A1 gene affects enzyme...

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Detalles Bibliográficos
Autores principales: Vukovic, M, Radlovic, N, Lekovic, Z, Vucicevic, K, Maric, N, Kotur, N, Gasic, V, Ugrin, M, Stojiljkovic, M, Dokmanovic, L, Zukic, B, Pavlovic, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sciendo 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231317/
https://www.ncbi.nlm.nih.gov/pubmed/30425912
http://dx.doi.org/10.2478/bjmg-2018-0012