Therapeutic Use of mTOR Inhibitors in Renal Diseases: Advances, Drawbacks, and Challenges

The mammalian (or mechanistic) target of rapamycin (mTOR) pathway has a key role in the regulation of a variety of biological processes pivotal for cellular life, aging, and death. Impaired activity of mTOR complexes (mTORC1/mTORC2), particularly mTORC1 overactivation, has been implicated in a pleth...

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Detalles Bibliográficos
Autores principales: Viana, Sofia D., Reis, Flávio, Alves, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231362/
https://www.ncbi.nlm.nih.gov/pubmed/30510618
http://dx.doi.org/10.1155/2018/3693625

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231362/
https://www.ncbi.nlm.nih.gov/pubmed/30510618
http://dx.doi.org/10.1155/2018/3693625

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