Cargando…

In vitro and in vivo quantification of chloroprocaine release from an implantable device in a piglet postoperative pain model

BACKGROUND: The pharmacokinetic properties and clinical advantages of the local anesthetic chloroprocaine are well known. Here, we studied the pharmacokinetic profile of a new hydrogel device loaded with chloroprocaine to investigate the potential advantages of this new strategy for postoperative pa...

Descripción completa

Detalles Bibliográficos
Autores principales:	De Gregori, Simona, De Gregori, Manuela, Bloise, Nora, Bugada, Dario, Molinaro, Mariadelfina, Filisetti, Claudia, Allegri, Massimo, Schatman, Michael E, Cobianchi, Lorenzo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231440/ https://www.ncbi.nlm.nih.gov/pubmed/30510443 http://dx.doi.org/10.2147/JPR.S180163

Ejemplares similares

Continuous wound infusion with chloroprocaine in a pig model of surgical lesion: drug absorption and effects on inflammatory response
por: Allegri, Massimo, et al.
Publicado: (2017)

Efficacy of intraventricular amikacin treatment in pan-resistant Pseudomonas aeruginosa postsurgical meningitis
por: Molinaro, Mariadelfina, et al.
Publicado: (2018)

From micro- to nanostructured implantable device for local anesthetic delivery
por: Zorzetto, Laura, et al.
Publicado: (2016)

Does a research group increase impact on the scientific community or general public discussion? Alternative metric-based evaluation
por: De Gregori, Manuela, et al.
Publicado: (2016)

Postoperative Analgesia in Neonates and Infants Using Epidural Chloroprocaine and Clonidine
por: Gibbs, Anna, et al.
Publicado: (2020)

Morphine metabolism, transport and brain disposition
por: De Gregori, Simona, et al.
Publicado: (2011)

Changes in total plasma and serum N-glycome composition and patient-controlled analgesia after major abdominal surgery
por: Gudelj, Ivan, et al.
Publicado: (2016)

Thoracic epidural infusion with chloroprocaine for postoperative analgesia following epicardial pacemaker placement in an infant
por: Kamata, Mineto, et al.
Publicado: (2014)

Immune function after major surgical interventions: the effect of postoperative pain treatment
por: Amodeo, Giada, et al.
Publicado: (2018)

Peritoneal Nebulization of Ropivacaine during Laparoscopic Cholecystectomy: Dose Finding and Pharmacokinetic Study
por: Allegri, Massimo, et al.
Publicado: (2017)

Hydroxychloroquine Blood Concentrations Can Be Clinically Relevant Also After Drug Discontinuation
por: De Gregori, Simona, et al.
Publicado: (2022)

Genetics and Opioids: Towards More Appropriate Prescription in Cancer Pain
por: Bugada, Dario, et al.
Publicado: (2020)

Continuous wound infusion of local anesthetic and steroid after major abdominal surgery: study protocol for a randomized controlled trial
por: Bugada, Dario, et al.
Publicado: (2015)

Inflammation-Based Scores: A New Method for Patient-Targeted Strategies and Improved Perioperative Outcome in Cancer Patients
por: Bugada, Dario, et al.
Publicado: (2014)

Effect of Femoral Nerve Block with Different Concentrations of Chloroprocaine on Early Postoperative Rehabilitation Training After Total Knee Arthroplasty
por: Li, Jiajia, et al.
Publicado: (2023)

Combining pain therapy with lifestyle: the role of personalized nutrition and nutritional supplements according to the SIMPAR Feed Your Destiny approach
por: De Gregori, Manuela, et al.
Publicado: (2016)

Pain assessment in animal models: do we need further studies?
por: Gigliuto, Carmelo, et al.
Publicado: (2014)

Bilateral Brachial Plexus Block Using Chloroprocaine For Surgery Of Bilateral Radial Fractures
por: Mangla, Chanchal, et al.
Publicado: (2019)

Second edition of SIMPAR’s “Feed Your Destiny” workshop: the role of lifestyle in improving pain management
por: De Gregori, Manuela, et al.
Publicado: (2018)

Bilateral Brachial Plexus Block Using Chloroprocaine For Surgery Of Bilateral Radial Fractures [Letter]
por: Hendriksen, Eva, et al.
Publicado: (2019)

Intrathecal chloroprocaine or hyperbaric prilocaine for ambulatory knee surgery? A prospective randomized study
por: Guntz, E, et al.
Publicado: (2021)

Randomized Controlled Study Comparing 2-Chloroprocaine and Bupivacaine for Spinal Anesthesia in Gynecological Surgeries
por: Thomas, Subin, et al.
Publicado: (2022)

Future Perspectives of ERAS: A Narrative Review on the New Applications of an Established Approach
por: Bugada, Dario, et al.
Publicado: (2016)

Epidural chloroprocaine bolus in emergency cesarean section-lessons learned from a near mishap
por: Goudra, Basavana G, et al.
Publicado: (2016)

Bilateral Brachial Plexus Block Using Chloroprocaine For Surgery Of Bilateral Radial Fractures [Response To Letter]
por: Mangla, Chanchal, et al.
Publicado: (2019)

Comparison of spinal anaesthesia with isobaric chloroprocaine and general anaesthesia for short duration ambulatory urological procedures
por: Ravi, Siddarth, et al.
Publicado: (2022)

Comparison of Intrathecal Chloroprocaine With Bupivacaine in Short Gynecological Procedures: A Randomized Double-Blind Study
por: Khurana, Bisman Jeet Kaur, et al.
Publicado: (2023)

From SIMPAR to CIMPARC: the evolution of international pain research and management
por: Allegri, Massimo, et al.
Publicado: (2018)

Comparing Spinal Chloroprocaine to Hyperbaric and Isobaric Bupivacaine for Total Hip and Knee Arthroplasties: A Retrospective Study
por: Gu, Lisa, et al.
Publicado: (2023)

A comparative study on the effect of addition of intrathecal buprenorphine to 2-chloroprocaine spinal anesthesia in short duration surgeries
por: Siddaiah, Jayaprakash, et al.
Publicado: (2019)

A survey assessing the need for spinal chloroprocaine to provide subarachnoid neuraxial anesthesia for short-duration surgeries in Canada
por: Szerb, Jennifer, et al.
Publicado: (2021)

A randomised, non-inferiority study of chloroprocaine 2% and ropivacaine 0.75% in ultrasound-guided axillary block
por: Sulyok, Irene, et al.
Publicado: (2021)

Spinal or Intravenous Dexmedetomidine for Spinal Anesthesia with Chloroprocaine in Ambulatory Knee Arthroscopies: A Double-Blind Randomized Trial
por: Breebaart, Margaretha B, et al.
Publicado: (2021)

A Randomized Clinical Trial Comparing Different Concentrations of Chloroprocaine with Lidocaine for Activating Epidural Analgesia During Labor
por: Zhu, Hai-Juan, et al.
Publicado: (2022)

Opioid-Free Anesthesia and Postoperative Outcomes in Cancer Surgery: A Systematic Review
por: Bugada, Dario, et al.
Publicado: (2022)

Effect of Preoperative Inflammatory Status and Comorbidities on Pain Resolution and Persistent Postsurgical Pain after Inguinal Hernia Repair
por: Bugada, Dario, et al.
Publicado: (2016)

Spinal Anesthesia Using Chloroprocaine is Safe, Effective, and Facilitates Earlier Discharge in Selected Fast-track Total Hip Arthroplasty
por: Herndon, Carl L., et al.
Publicado: (2020)

A Study to Evaluate Intrathecal 1% Chloroprocaine and 0.5% Levobupivacaine in Perianal Surgeries: A Prospective Randomized Study
por: Bhaskara, B., et al.
Publicado: (2020)

A Comparative Study of Dexmedetomidine versus Nalbuphine Used as an Adjuvant to Chloroprocaine for Daycare Surgeries Performed under Subarachnoid Block
por: Gupta, Priyamvada, et al.
Publicado: (2022)

Perioperative Outcomes in Patients Who Received Spinal Chloroprocaine for Total Hip or Knee Arthroplasty—Consecutive Case Series Study
por: Alhefeiti, Khaleifah, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_0h3ottc3bknl1ifceg0kb7joov