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Identification of a novel mutation in APP gene in a Thai subject with early-onset Alzheimer’s disease
INTRODUCTION: Early-onset Alzheimer’s disease (AD) accounts for than less 1% of all AD cases, with large variation in the reported genetic contributions of known dementia genes. Mutations in the amyloid precursor protein (APP) gene were the first to be recognized as the cause of AD. METHODS: Here, a...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231518/ https://www.ncbi.nlm.nih.gov/pubmed/30510423 http://dx.doi.org/10.2147/NDT.S180174 |