SUMO-1 modification of FEN1 facilitates its interaction with Rad9–Rad1–Hus1 to counteract DNA replication stress

Human flap endonuclease 1 (FEN1) is a structure-specific, multi-functional endonuclease essential for DNA replication and repair. We and others have shown that during DNA replication, FEN1 processes Okazaki fragments via its interaction with the proliferating cell nuclear antigen (PCNA). Alternative...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Xiaoli, Shi, Rongyi, Zheng, Li, Guo, Zhigang, Wang, Liangyan, Zhou, Mian, Zhao, Ye, Tian, Bing, Truong, Khue, Chen, Yuan, Shen, Binghui, Hua, Yuejin, Xu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231531/
https://www.ncbi.nlm.nih.gov/pubmed/30184152
http://dx.doi.org/10.1093/jmcb/mjy047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231531/
https://www.ncbi.nlm.nih.gov/pubmed/30184152
http://dx.doi.org/10.1093/jmcb/mjy047

Ejemplares similares