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MicroRNA-146a reduces MHC-II expression via targeting JAK/STAT-signaling in dendritic cells after stem cell transplantation

Acute Graft-versus-host disease (GVHD) is a major immunological complication after allogeneic hematopoietic cell transplantation and a better understanding of the molecular regulation of the disease could help to develop novel targeted therapies. Here we found that a G/C polymorphism within the huma...

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Detalles Bibliográficos
Autores principales: Stickel, Natalie, Hanke, Kathrin, Marschner, Dominik, Prinz, Gabriele, Köhler, Martin, Melchinger, Wolfgang, Pfeifer, Dietmar, Schmitt-Graeff, Annette, Brummer, Tilman, Heine, Annkristin, Brossart, Peter, Wolf, Dominik, von Bubnoff, Nikolas, Finke, Jürgen, Duyster, Justus, Ferrara, James, Salzer, Ulrich, Zeiser, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231537/
https://www.ncbi.nlm.nih.gov/pubmed/28484267
http://dx.doi.org/10.1038/leu.2017.137