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The phosphorylation of sorting nexin 5 at serine 226 regulates retrograde transport and macropinocytosis

Sorting nexin 5 (SNX5), a member of sorting nexin family, plays an important role in membrane trafficking, including the retrograde trafficking of the cation independent mannose 6-phosphate receptor (CI-M6PR) and macropinocytosis. Using ESI-LCMS/MS analysis, we confirmed that SNX5 serine 226 is phos...

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Detalles Bibliográficos
Autores principales: Itai, Nao, Shimazu, Tsukasa, Kimura, Takayuki, Ibe, Issei, Yamashita, Ryo, Kaburagi, Yasushi, Dohi, Taeko, Tonozuka, Takashi, Takao, Toshifumi, Nishikawa, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231649/
https://www.ncbi.nlm.nih.gov/pubmed/30419003
http://dx.doi.org/10.1371/journal.pone.0207205