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Age-related differences in IL-1 signaling and capsule serotype affect persistence of Streptococcus pneumoniae colonization

Young age is a risk factor for prolonged colonization by common pathogens residing in their upper respiratory tract (URT). Why children present with more persistent colonization is unknown and there is relatively little insight into the host-pathogen interactions that contribute to persistent coloni...

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Detalles Bibliográficos
Autores principales: Kuipers, Kirsten, Lokken, Kristen L., Zangari, Tonia, Boyer, Mark A., Shin, Sunny, Weiser, Jeffrey N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231672/
https://www.ncbi.nlm.nih.gov/pubmed/30379943
http://dx.doi.org/10.1371/journal.ppat.1007396