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Molecular characterization of breast and lung tumors by integration of multiple data types with functional sparse-factor analysis

Effective cancer treatment is crucially dependent on the identification of the biological processes that drive a tumor. However, multiple processes may be active simultaneously in a tumor. Clustering is inherently unsuitable to this task as it assigns a tumor to a single cluster. In addition, the wi...

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Detalles Bibliográficos
Autores principales: Bismeijer, Tycho, Canisius, Sander, Wessels, Lodewyk F. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231682/
https://www.ncbi.nlm.nih.gov/pubmed/30379847
http://dx.doi.org/10.1371/journal.pcbi.1006520