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An open label randomized clinical trial comparing the safety and effectiveness of one, two or three weekly pentamidine isethionate doses (seven milligrams per kilogram) in the treatment of cutaneous leishmaniasis in the Amazon Region

BACKGROUND: American Cutaneous Leishmaniasis (ACL), a vector borne disease, is caused by various species of Leishmania and in the Amazonas, Leishmania guyanensis is predominant. The recommended drugs for treatment of cutaneous leishmaniasis (CL) in Brazil are pentavalent antimonials, pentamidine ise...

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Detalles Bibliográficos
Autores principales: Gadelha, Ellen Priscilla Nunes, Ramasawmy, Rajendranath, da Costa Oliveira, Bruna, Morais Rocha, Nágila, de Oliveira Guerra, Jorge Augusto, Allan Villa Rouco da Silva, George, Gabrielle Ramos de Mesquita, Tirza, Chrusciak Talhari Cortez, Carolina, Chrusciak Talhari, Anette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231690/
https://www.ncbi.nlm.nih.gov/pubmed/30379814
http://dx.doi.org/10.1371/journal.pntd.0006850