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Active presynaptic ribosomes in the mammalian brain, and altered transmitter release after protein synthesis inhibition

Presynaptic neuronal activity requires the localization of thousands of proteins that are typically synthesized in the soma and transported to nerve terminals. Local translation for some dendritic proteins occurs, but local translation in mammalian presynaptic nerve terminals is difficult to demonst...

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Detalles Bibliográficos
Autores principales: Scarnati, Matthew S, Kataria, Rahul, Biswas, Mohana, Paradiso, Kenneth G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231766/
https://www.ncbi.nlm.nih.gov/pubmed/30375975
http://dx.doi.org/10.7554/eLife.36697