Marked Reduction in the Striatal Dopamine Transporter Uptake During the Early Stage of Motor Symptoms in Patients with the MAPT N279K Mutation

We herein report two patients harboring the mutation N279K in microtubule-associated protein tau (MAPT), who showed parkinsonism with a disease duration within three years from the onset, evaluated by dopamine transporter (DAT) [(123)I]N-ω-fluoroprophyl-2β-carbomethoxy-3β-(4-iodophenyl) tropane sing...

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Detalles Bibliográficos
Autores principales: Takeshige, Haruka, Nakayama, Sachiko, Nishioka, Kenya, Li, Yuanzhe, Motoi, Yumiko, Hattori, Nobutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232026/
https://www.ncbi.nlm.nih.gov/pubmed/29877269
http://dx.doi.org/10.2169/internalmedicine.0454-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232026/
https://www.ncbi.nlm.nih.gov/pubmed/29877269
http://dx.doi.org/10.2169/internalmedicine.0454-17

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