Clinical implications of changes in the diversity of c-MYC copy number variation after neoadjuvant chemotherapy in breast cancer

Chemotherapy can alter the makeup of a tumor cell population by exerting selection pressure. We examined the change in Shannon index, a mathematical diversity measure used in ecology, for c-MYC copy number variation (CNV) after neoadjuvant chemotherapy and evaluated its clinical significance in brea...

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Detalles Bibliográficos
Autores principales: Chung, Yul Ri, Kim, Hyun Jeong, Kim, Milim, Ahn, Soomin, Park, So Yeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232091/
https://www.ncbi.nlm.nih.gov/pubmed/30420657
http://dx.doi.org/10.1038/s41598-018-35072-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232091/
https://www.ncbi.nlm.nih.gov/pubmed/30420657
http://dx.doi.org/10.1038/s41598-018-35072-5

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