High-throughput three-dimensional chemotactic assays reveal steepness-dependent complexity in neuronal sensation to molecular gradients

Many cellular programs of neural development are under combinatorial regulation by different chemoattractive or chemorepulsive factors. Here, we describe a microfluidic platform that utilizes well-controlled three-dimensional (3D) diffusion to generate molecular gradients of varied steepness in a la...

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Detalles Bibliográficos
Autores principales: Xu, Zhen, Fang, Peilin, Xu, Bingzhe, Lu, Yufeng, Xiong, Jinghui, Gao, Feng, Wang, Xin, Fan, Jun, Shi, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232128/
https://www.ncbi.nlm.nih.gov/pubmed/30420609
http://dx.doi.org/10.1038/s41467-018-07186-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232128/
https://www.ncbi.nlm.nih.gov/pubmed/30420609
http://dx.doi.org/10.1038/s41467-018-07186-x

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