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High-throughput three-dimensional chemotactic assays reveal steepness-dependent complexity in neuronal sensation to molecular gradients

Many cellular programs of neural development are under combinatorial regulation by different chemoattractive or chemorepulsive factors. Here, we describe a microfluidic platform that utilizes well-controlled three-dimensional (3D) diffusion to generate molecular gradients of varied steepness in a la...

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Detalles Bibliográficos
Autores principales:	Xu, Zhen, Fang, Peilin, Xu, Bingzhe, Lu, Yufeng, Xiong, Jinghui, Gao, Feng, Wang, Xin, Fan, Jun, Shi, Peng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232128/ https://www.ncbi.nlm.nih.gov/pubmed/30420609 http://dx.doi.org/10.1038/s41467-018-07186-x

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